49003 HPLC Plasma Calibration Standard Benzodiazepines TCA

Plasma Calibration Standard Benzodiazepines/TCA

Order no.: 49003
  • Amitriptyline
  • Bromazepam
  • Chlordiazepoxide
  • Clobazam
  • Clomipramine
  • Clonazepam
  • Clozapine
  • Desipramine
  • Diazepam
  • Doxepin
  • Flunitrazepam
  • Imipramine
  • Maprotiline
  • Nitrazepam
  • Norclomipramine
  • Norclozapine
  • Nordiazepam
  • Nordoxepin
  • Nortriptyline
  • Oxazepam
  • Trimipramine


Plasma Calibration Standard Benzodiazepines/TCA, lyophilised

This lyophilised calibrator from Chromsystems is based on human plasma and should be used according to the instruction manual. It is designed to calibrate the measurement method in clinical diagnostics for the quantitative determination of benzodiazepines and tricyclic antidepressants in serum/plasma. While following the instructions the calibrator should be handled and measured in the same manner as a patient specimen.

Technical Data

Method of Analysis



5 x 2.5 ml (lyoph.)


Amitriptyline, Bromazepam, Chlordiazepoxide, Clobazam, Clomipramine, Clonazepam, Clozapine, Desipramine, Diazepam, Doxepin, Flunitrazepam, Imipramine, Maprotiline, Nitrazepam, Norclomipramine, Norclozapine, Nordiazepam, Nordoxepin, Nortriptyline, Oxazepam, Trimipramine


Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

Substance - Tricyclic AntidepressantsUnitValue
Norclozapine ng/ml 288
Clozapine ng/ml 494
Nordoxepin ng/ml 167
Doxepin ng/ml 166
Desipramine ng/ml 198
Imipramine ng/ml 193
Nortriptyline ng/ml 199
Maprotiline ng/ml 196
Amitriptyline ng/ml 190
Trimipramine ng/ml 171
Norclomipramine ng/ml 177
Clomipramine ng/ml 173


Substance - BenzodiazepinesUnitValue
Chlordiazepoxide ng/ml 1010
Bromazepam ng/ml 133
Oxazepam ng/ml 861
Nitrazepam ng/ml 99.3
Clonazepam ng/ml 44.2
Flunitrazepam ng/ml 32.6
Nordiazepam ng/ml 531
Clobazam ng/ml 324
Diazepam ng/ml 904


Carefully remove the metal seal and rubber stopper from the vials. Add exactly 2.5 ml of distilled water into each vial. Return the stopper and incubate for 10 to 15 minutes at room temperature. Swirl the vials to dissolve the contents until homogeneity.

Storage conditions

Stored at +2 to +8 °C and unopened, the lyophilised calibrator is stable until the expiry date specified on the vial labels. The reconstituted calibrator can be stored up to 1 week light protected and tightly capped at +2 to +8 C. If the calibrator cannot be used within this period, it should be aliquoted and stored frozen below -18 °C (up to 3 months). For more details about storage conditions please check your instruction manual.