0240 0241 0242 LCMS TDM Series A controls benzodiazepines2

MassCheck® Benzodiazepines 2 Plasma Controls

   
  • Alprazolam
  • Bromazepam
  • Clonazepam
  • Desalkylflurazepam
  • Flunitrazepam
  • Flurazepam
  • Lorazepam
  • Lormetazepam
  • Nitrazepam
  • Triazolam

Order no.: 0240/0241/0242

Product Name Qty
MassCheck® Benzodiazepines 2 Plasma Control, Level I
Order no.: 0241
MassCheck® Benzodiazepines 2 Plasma Control, Level II
Order no.: 0242
MassCheck® Benzodiazepines 2 Plasma Control, Bi-Level (I+II)
Order no.: 0240

Description

MassCheck® Benzodiazepines 2 Plasma Controls, lyophilised

0240 MassCheck® Benzodiazepines 2 Plasma Control, Bi-Level I + II (lyoph.), 2 x 5 x 1 ml
0241 MassCheck® Benzodiazepines 2 Plasma Control, Level I (lyoph.), 5 x 1 ml
0242 MassCheck® Benzodiazepines 2 Plasma Control, Level II (lyoph.), 5 x 1 ml

These lyophilised quality controls from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to monitor the accuracy and precision of analytical procedures in clinical diagnostics for the quantitative determination of benzodiazepines 2 in serum/plasma. While following the instructions the controls should be handled and measured in the same manner as a patient specimen.

Technical Data

Method of Analysis

LC-MS/MS

Parameter

Alprazolam, Bromazepam, Clonazepam, Desalkylflurazepam, Flunitrazepam, Flurazepam, Lorazepam, Lormetazepam, Nitrazepam, Triazolam

Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

SubstanceValue [µg/l]
Level I
Range [µg/l]
Level I
Value [µg/l]
Level II
Range [µg/l]
Level II
Alprazolam 8.89 7.11-10.7 41.0 32.8-49.2
Bromazepam 63.7 51.0-76.5 163 130-195
Clonazepam 17.4 13.9-20.9 64.5 51.6-77.4
Desalkylflurazepam 22.4 17.9-26.9 114 91.5-137
Flunitrazepam 7.09 5.67-8.51 27.2 21.8-32.6
Flurazepam 7.69 6.15-9.23 30.4 24.3-36.5
Lorazepam 38.9 31.1-46.7 195 156-234
Lormetazepam 6.10 4.88-7.32 21.4 17.1-25.7
Nitrazepam 42.3 33.9-50.8 141 112-169
Triazolam 3.90 3.12-4.68 18.4 14.7-22.1

Reconstitution

Carefully remove the rubber stopper from the vials. Add exactly 1.0 ml of distilled water into each vial. Return the stopper and incubate for 10 to 15 minutes at room temperature. Swirl the vials to dissolve the contents until homogeneity.

Storage conditions

Stored below -18 °C and unopened, the lyophilised controls are stable until the expiry date specified on the vial labels. The reconstituted controls can be stored up to 1 week light protected and tightly capped at +2 to +8 C. If the controls cannot be used within this period, they should be aliquoted and stored frozen below -18 °C (up to 3 months). For more details about storage conditions please check your instruction manual.