0237 0238 0239 LCMS TDM Series A controls benzodiazepines1

MassCheck® Benzodiazepines 1 Plasma Controls

   
  • 1-OH-midazolam
  • Chlordiazepoxide
  • Clobazam
  • Demoxepam
  • Diazepam
  • Medazepam
  • Midazolam
  • Norclobazam
  • Nordiazepam
  • Oxazepam
  • Prazepam
  • Temazepam
  • Tetrazepam

Order no.: 0237/0238/0239

Product Name Qty
MassCheck® Benzodiazepines 1 Plasma Control, Level I
Order no.: 0238
MassCheck® Benzodiazepines 1 Plasma Control, Level II
Order no.: 0239
MassCheck® Benzodiazepines 1 Plasma Control, Bi-Level (I+II)
Order no.: 0237

Description

MassCheck® Benzodiazepines 1 Plasma Controls, lyophilised

0237 MassCheck® Benzodiazepines 1 Plasma Control, Bi-Level I + II (lyoph.), 2 x 5 x 1 ml
0238 MassCheck® Benzodiazepines 1 Plasma Control, Level I (lyoph.), 5 x 1 ml
0239 MassCheck® Benzodiazepines 1 Plasma Control, Level II (lyoph.), 5 x 1 ml

 

These lyophilised quality controls from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to monitor the accuracy and precision of analytical procedures in clinical diagnostics for the quantitative determination of benzodiazepines 1 in serum/plasma. While following the instructions the controls should be handled and measured in the same manner as a patient specimen.

Technical Data

Method of Analysis

LC-MS/MS

Parameter

1-OH-midazolam, Chlordiazepoxide, Clobazam, Demoxepam, Diazepam, Medazepam, Midazolam, Norclobazam, Nordiazepam, Oxazepam, Prazepam, Temazepam, Tetrazepam

Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

SubstanceValue [µg/l]
Level I
Range [µg/l]
Level I
Value [µg/l]
Level II
Range [µg/l]
Level II
Chlordiazepoxide 504 403-605 1608 1286-1930
Clobazam 122 97.6-146 416 333-499
Demoxepam 495 396-594 1766 1413-2119
Diazepam 230 184-276 1198 958-1438
Medazepam 129 103-155 410 328-492
Midazolam 31.9 25.5-38.3 152 122-182
1-OH-Midazolam 36.5 29.2-43.8 165 132-198
Norclobazam 1152 922-1382 3332 2666-3998
Nordiazepam 155 124-186 1270 1016-1524
Oxazepam 333 266-400 1694 1355-2033
Prazepam 240 192-288 598 478-718
Temazepam 115 92.3-138 878 702-1054
Tetrazepam 119 94.9-142 642 513.6-770

Reconstitution

Carefully remove the metal seal and rubber stopper from the vials. Add exactly 1.0 ml of distilled water into each vial. Return the stopper and incubate for 10 to 15 minutes at room temperature. Swirl the vials to dissolve the contents until homogeneity.

Storage conditions

Stored below -18 °C and unopened, the lyophilised controls are stable until the expiry date specified on the vial labels. The reconstituted controls can be stored up to 1 week light protected and tightly capped at +2 to +8 C. If the controls cannot be used within this period, they should be aliquoted and stored frozen below -18 °C (up to 3 months). For more details about storage conditions please check your instruction manual.