MassCheck® Antimycotic Drugs Plasma Controls

MassCheck® Antimycotic Drugs Plasma Controls

   

Order no.: 0252/RUO; 0253/RUO; 0254/RUO

MassTox® Series A

Product Name Qty
MassCheck® Antimycotic Drugs Plasma Control, Level I
Order no.: 0253/RUO
MassCheck® Antimycotic Drugs Plasma Control, Level II
Order no.: 0254/RUO
MassCheck® Antimycotic Drugs Plasma Control, Bi-Level (I+II)
Order no.: 0252/RUO

Description

MassCheck® Antimycotic Drugs Plasma Controls, lyophilised
For MassTox® Series A Parameter Set Antimycotic Drugs in Serum/Plasma.

0252/RUO MassCheck® Antimycotic Drugs Plasma Control, Bi-Level I + II (lyoph.), 2 x 5 x 1 ml
0253/RUO MassCheck® Antimycotic Drugs Plasma Control, Level I (lyoph.), 5 x 1 ml
0254/RUO MassCheck® Antimycotic Drugs Plasma Control, Level II (lyoph.), 5 x 1 ml

These lyophilised Chromsystems controls are based on human plasma and should be used according to the instruction manual. They are designed to monitor the accuracy and precision of analytical procedures for the quantitative determination of antimycotic drugs. While following the instructions the controls should be handled and measured in the same manner as research samples.

Technical Data

Method of Analysis

LC-MS/MS

Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly.

SubstanceSuggested value [mg/l]
Level I
Suggested range [mg/l]
Level I
Suggested value [mg/l]
Level II
Suggested range [mg/l]
Level II
Fluconazole 2.40 1.92-2.88 13.6 10.9-16.4
5-Flucytosine 18.1 14.5-21.8 77.0 61.6-92.4
Hydroxyitraconazole 0.460 0.368-0.552 1.77 1.42-2.12
Itraconazole 0.370 0.296-0.444 1.42 1.13-1.70
Ketoconazole 1.26 1.01-1.51 8.95 7.16-10.7
Posaconazole 0.675 0.540-0.810 3.61 2.89-4.33
Voriconazole 0.99 0.788-1.18 4.65 3.72-5.58

Reconstitution

Carefully remove the metal seal and rubber stopper from the vials. (Caution when removing the metal seal: risk of injuries due to sharp cutting edges!). Add exactly 1.0 ml of distilled water into each vial. Return the stopper and incubate for 10 to 15 minutes at room temperature. Swirl the vials to dissolve the contents until homogeneity.

Storage conditions

Stored below -18 °C and unopened, the lyophilised controls are stable until the expiry date specified on the vial labels. The reconstituted controls can be stored up to 3 weeks tightly capped at +2 to +8 C. If the controls cannot be used within this period, they should be aliquoted and stored frozen below -18 °C (up to 3 months). For more details about storage conditions please check your instruction manual.