TDM Series A controls antidepressants2_psychostimulants_XT 0231XT_0231XT_0232XT LCMS

MassCheck® Antidepressants 2/ Psychostimulants/EXTENDED Plasma Controls

   
  • Atomoxetine
  • Bupropion
  • Clomethiazole
  • Dosulepin
  • erythro-Dihydrobupropion
  • Hydroxybupropion
  • Methylphenidate
  • Mianserin
  • Milnacipran
  • Moclobemide
  • N-Desmethyldosulepin
  • Opipramol
  • Reboxetine
  • Ritalinic acid
  • threo-Dihydrobupropion
  • Tianeptine
  • Tranylcypromine
  • Trazodone
  • Vilazodone
  • Vortioxetine

Order no.: 0230/XT; 0231/XT; 0232/XT

Product Name Qty
MassCheck® Antidepressants 2 /Psychostimulants/EXTENDED Plasma Control, Level I
Order no.: 0231/XT
MassCheck® Antidepressants 2 /Psychostimulants/EXTENDED Plasma Control, Level II
Order no.: 0232/XT
MassCheck® Antidepressants 2 /Psychostimulants/EXTENDED Plasma Control, Bi-Level (I+II)
Order no.: 0230/XT

Description

MassCheck® Antidepressants 2/Psychostimulants/EXTENDED Plasma Controls, lyophilised.

0230/XT MassCheck® Antidepressants 2/Psychostimulants/EXTENDED Plasma Control, Bi-Level I + II (lyoph.), 2 x 5 x 1 ml
0231/XT MassCheck® Antidepressants 2/Psychostimulants/EXTENDED Plasma Control, Level I (lyoph.), 5 x 1 ml
0232/XT MassCheck® Antidepressants 2/Psychostimulants/EXTENDED Plasma Control, Level II (lyoph.), 5 x 1 ml

These lyophilised quality controls from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to monitor the accuracy and precision of analytical procedures in clinical diagnostics for the quantitative determination of antidepressants 2 and psychostimulants in serum/plasma. While following the instructions the controls should be handled and measured in the same manner as a patient specimen.

Technical Data

Method of Analysis

LC-MS/MS

Parameter

Atomoxetine, Bupropion, Clomethiazole, Dosulepin, erythro-Dihydrobupropion, Hydroxybupropion, Methylphenidate, Mianserin, Milnacipran, Moclobemide, N-Desmethyldosulepin, Opipramol, Reboxetine, Ritalinic acid, threo-Dihydrobupropion, Tianeptine, Tranylcypromine, Trazodone, Vilazodone, Vortioxetine

Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

Substance Unit Target value
Level I
Target range
Level I
Target value
Level II
Target range
Level II
Atomoxetine µg/l 129 103 -155 890 712 -1068
Clomethiazol µg/l 620 496 -744 4673 3738 -5608
N-Desmethyldosulepin µg/l 83.9 67.1 -101 215 172 -258
Dosulepin µg/l 49.0 39.2 -58.8 339 271 -407
Methylphenidate µg/l 10.3 8.24 -12.4 57.4 45.9 -68.9
Mianserin µg/l 23.9 19.1 -28.7 128 102 -154
Milnacipran µg/l 58.3 46.6 -70 336 269 -403
Moclobemide µg/l 389 311 -467 2185 1748 -2622
Opipramol µg/l 91.7 73.4 -110 541 433 -649
Reboxetine µg/l 56.0 44.8 -67.2 297 238 -356
Ritalinic acid µg/l 61.4 49.1 -73.7 255 204 -306
Tianeptine µg/l 54.2 43.4 -65 326 261 -391
Tranylcypromine µg/l 69.0 55.2 -82.8 561 449 -673
Trazodone µg/l 515 412 -618 2165 1732 -2598
Vilazodone µg/l 29.8 23.8 -35.8 86.1 68.9 -103
Vortioxetine µg/l 15.8 12.6 -19 83.4 66.7 -100
Bupropion µg/l 35.9 28.7 -43.1 272 218 -326
erythro-Dihydrobupropion µg/l 34.5 27.6 -41.4 261 209 -313
Hydroxybupropion µg/l 234 187 -281 1875 1500 -2250
threo-Dihydrobupropion µg/l 178 142 -214 1251 1001 -1501

Reconstitution

Carefully remove the rubber stopper from the vials. Add exactly 1.0 ml of distilled water into each vial. Return the stopper and incubate for 10 to 15 minutes at room temperature. Swirl the vials to dissolve the contents until homogeneity.

Storage conditions

Stored below -18 °C and unopened, the lyophilised controls are stable until the expiry date specified on the vial labels. The reconstituted controls can be stored up to 1 day light protected and tightly capped at +2 to +8 C. If the controls cannot be used within this period, they should be aliquoted and stored frozen below -18 °C (up to 3 months). For more details about storage conditions please check your instruction manual.