MassCheck® Anti-HIV Drugs Plasma Controls

MassCheck® Anti-HIV Drugs Plasma Controls

   

Order no.: 0261/RUO; 0262/RUO; 0263/RUO

MassTox® Series A

Product Name Qty
MassCheck® Anti-HIV Drugs Plasma Control, Level I
Order no.: 0262/RUO
MassCheck® Anti-HIV Drugs Plasma Control, Level II
Order no.: 0263/RUO
MassCheck® Anti-HIV Drugs Plasma Control, Bi-Level (I+II)
Order no.: 0261/RUO

Description

MassCheck® Anti-HIV Drugs Plasma Controls, lyophilised
For MassTox® Series A Parameter Set Anti-HIV Drugs in Serum/Plasma.

0261/RUO MassCheck® Anti-HIV Drugs Plasma Control, Bi-Level I + II (lyoph.), 2 x 5 x 1 ml
0262/RUO MassCheck® Anti-HIV Drugs Plasma Control, Level I (lyoph.), 5 x 1 ml
0263/RUO MassCheck® Anti-HIV Drugs Plasma Control, Level II (lyoph.), 5 x 1 ml

These lyophilised Chromsystems controls are based on human plasma and should be used according to the instruction manual. They are designed to monitor the accuracy and precision of analytical procedures for the quantitative determination of anti-HIV drugs. While following the instructions the controls should be handled and measured in the same manner as research samples.

 

Technical Data

Method of Analysis

LC-MS/MS

Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly.

SubstanceSuggested value [µg/l]
Level I
Suggested range [µg/l]
Level I
Suggested value [µg/l]
Level II
Suggested range [µg/l]
Level II
Group 1
Amprenavir 463 371-556 2065 1652-2478
Darunavir 517 414-621 4033 3227-4840
Delavirdine 1556 1245-1867 7170 5736-8604
Maraviroc 136 109-164 946 757-1135
Nevirapine 2864 2291-3437 5831 4664-6997
Raltegravir 91.6 73.3-110 490 392-588
Group 2
Efavirenz 1133 906-1359 3531 2825-4237
Indinavir 320 256-383 2743 2195-3292
Nelfinavir 862 690-1035 2121 1697-2545
M8-Nelfinavir 349 279-418 1373 1098-1647
Rilpivirine 73.7 59.0-88.4 270 216-324
Saquinavir 117 93.4-140 671 537-806
Group 3
Atazanavir 281 225-337 1992 1594-2391
Elvitegravir 270 216-323 980 784-1175
Etravitrine 385 308-462 2690 2152-3228
Lopinavir 1747 1398-2097 8219 6575-9862
Ritonavir 1333 1066-1599 9885 7908-11862
Tipranavir 13912 11129-16694 39934 31948-47921

Reconstitution

Carefully remove the metal seal and rubber stopper from the vials. (Caution when removing the metal seal: risk of injuries due to sharp cutting edges!). Add exactly 1.0 ml of distilled water into each vial. Return the stopper and incubate for 10 to 15 minutes at room temperature. Swirl the vials to dissolve the contents until homogeneity.

Storage conditions

Stored below -18 °C and unopened, the lyophilised controls are stable until the expiry date specified on the vial labels. The reconstituted controls can be stored up to 2 weeks light protected and tightly capped at +2 to +8 C. If the controls cannot be used within this period, they should be aliquoted and stored frozen below -18 °C (up to 3 months). For more details about storage conditions please check your instruction manual.

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