Antibiotics Plasma Controls 0182 0183 0184

MassCheck® Amino Acid Analysis Plasma Controls

   
  • 1-Methylhistidine
  • 3-Methylhistidine
  • 4-Hydroxyproline
  • Acetyltyrosine
  • Adenosylhomocysteine
  • Alanine
  • Allo-Isoleucine
  • Anserine
  • Arginine
  • Argininosuccinic acid
  • Asparagine
  • Aspartic acid
  • Carnosine
  • Citrulline
  • Cystathionine
  • Cysteine S-sulfate
  • Cystine
  • Ethanolamine
  • Glutamic acid
  • Glutamine
  • Glycine
  • Histidine
  • Homocitrulline
  • Homocystine
  • Hydroxylysine
  • Isoleucine
  • Leucine
  • Lysine
  • Methionine
  • Ornithine
  • Phenylalanine
  • Phosphoethanolamine
  • Phosphoserine
  • Pipecolic acid
  • Proline
  • Saccharopine
  • Sarcosine
  • Serine
  • Taurine
  • Threonine
  • Tryptophan
  • Tyrosine
  • Valine
  • α-Aminoadipic acid
  • α-Aminobutyric acid
  • β-Alanine
  • β-Aminoisobutyric acid
  • γ-Aminobutyric acid

Order no.: 0471/0472/0473

Product Name Qty
MassCheck® Amino Acid Analysis Plasma Control, Level I
Order no.: 0471
MassCheck® Amino Acid Analysis Plasma Control, Level II
Order no.: 0472
MassCheck® Amino Acid Analysis Plasma Control, Level III
Order no.: 0473

Description

Antibiotics Plasma Controls, lyophilised.

0183 Antibiotics Plasma Control, Level I (lyoph.), 5 x 1 ml
0184 Antibiotics Plasma Control, Level II (lyoph.), 5 x 1 ml

These lyophilised quality controls from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to monitor the accuracy and precision of analytical procedures in clinical diagnostics for the quantitative determination of antibiotics in serum/plasma. While following the instructions the controls should be handled and measured in the same manner as a patient specimen.

Technical Data

Method of Analysis

LC-MS/MS

Parameter

1-Methylhistidine, 3-Methylhistidine, 4-Hydroxyproline, Acetyltyrosine, Adenosylhomocysteine, Alanine, Allo-Isoleucine, Anserine, Arginine, Argininosuccinic acid, Asparagine, Aspartic acid, Carnosine, Citrulline, Cystathionine, Cysteine S-sulfate, Cystine, Ethanolamine, Glutamic acid, Glutamine, Glycine, Histidine, Homocitrulline, Homocystine, Hydroxylysine, Isoleucine, Leucine, Lysine, Methionine, Ornithine, Phenylalanine, Phosphoethanolamine, Phosphoserine, Pipecolic acid, Proline, Saccharopine, Sarcosine, Serine, Taurine, Threonine, Tryptophan, Tyrosine, Valine, α-Aminoadipic acid, α-Aminobutyric acid, β-Alanine, β-Aminoisobutyric acid, γ-Aminobutyric acid

Concentrations

Please note: All concentrations shown here are exemplatory. They do not reflect real data for the described products. Actual concentrations depend on the production lot of each product and can exclusively be found in the product information leaflet. Please ask for these product information leaflets or download them from the service site of the Chromsystems website.

 

NEW: An Excel file with the data from the product information leaflet is now newly available in the "Product Downloads" section below (for registered customers only). This eliminates manual data entry of large data sets.

Substance

Control Level I
0471

Target Value

(µmol/l)

Range (µmol/l)

Target Value

(mg/l)

Range (mg/l)

1-Methylhistidine

2.57

2.06

-

3.08

0.435

0.348

-

0.522

α-Aminobutyric acid

4.62

3.69

-

5.54

0.476

0.381

-

0.571

β-Aminoisobutyric acid

4.77

3.82

-

5.73

0.492

0.394

-

0.591

3-Methylhistidine

7.28

5.82

-

8.73

1.23

0.985

-

1.48

4-Hydroxy-Proline

9.92

7.94

-

11.9

1.30

1.04

-

1.56

Acetyltyrosine

5.13

4.10

-

6.15

1.14

0.916

-

1.37

Adenosylhomocysteine

3.46

2.77

-

4.16

1.33

1.06

-

1.60

Alanine

199

159

-

239

17.7

14.2

-

21.3

Allo-Isoleucine

3.57

2.86

-

4.29

0.469

0.375

-

0.563

α-Aminoadipic acid

6.22

4.98

-

7.46

1.00

0.802

-

1.20

Anserine

4.81

3.85

-

5.77

1.16

0.924

-

1.39

Arginine

10.8

8.63

-

12.9

1.88

1.50

-

2.25

Argininosuccinic acid

2.94

2.35

-

3.53

0.854

0.683

-

1.03

Asparagine

26.8

21.4

-

32.1

3.56

2.85

-

4.28

Aspartic acid

23.1

18.5

-

27.7

3.05

2.44

-

3.66

β-Alanine

13.0

10.4

-

15.5

1.15

0.923

-

1.38

Carnosine

9.61

7.69

-

11.5

2.17

1.74

-

2.61

Citrulline

15.9

12.7

-

19.1

2.79

2.23

-

3.35

Cystathionine

6.07

4.86

-

7.29

1.35

1.08

-

1.62

Cysteinesulfate

12.6

10.1

-

15.2

2.54

2.03

-

3.05

Cystine

10.7

8.54

-

12.8

2.57

2.05

-

3.08

Ethanolamine

15.3

12.3

-

18.4

0.935

0.748

-

1.12

γ-Aminobutyric acid

4.74

3.79

-

5.69

0.489

0.391

-

0.586

Glutamine

358

286

-

429

52.6

42.1

-

63.1

Glutamic acid

57.3

45.8

-

68.7

8.37

6.70

-

10.0

Glycine

192

154

-

231

14.4

11.5

-

17.3

Histidine

44.9

35.9

-

53.9

6,97

5.58

-

8.37

Homocitrulline

9.85

7.88

-

11.8

1.86

1.49

-

2.24

Homocystine

4.11

3.29

-

4.93

1.10

0.883

-

1.32

Hydroxylysine

4.97

3.97

-

5.96

0.806

0.645

-

0.967

Isoleucine

23.0

18.4

-

27.6

3.02

2.41

-

3.62

Leucine

50.3

40.2

-

60.3

6.59

5.27

-

7.91

Lysine

27.4

21.9

-

32.9

4.01

3.21

-

4.81

Methionine

8.51

6.80

-

10.2

1.27

1.02

-

1.52

Ornithine

17.0

13.6

-

20.4

2.24

1.79

-

2.69

Phenylalanine

40.3

32.2

-

48.3

6.65

5.32

-

7.98

Phosphoethanolamine

10.7

8.53

-

12.8

1.50

1.20

-

1.81

Phosphoserine

6.34

5.08

-

7.61

1.17

0.939

-

1.41

Pipecolic acid

2.03

1.62

-

2.43

0.262

0.209

-

0.314

Proline

63.4

50.7

-

76.1

7.30

5.84

-

8.76

Saccharopine

4.78

3.83

-

5.74

1.32

1.06

-

1.59

Sarcosine

4.11

3.29

-

4.94

0.366

0.293

-

0.440

Serine

128

102

-

153

13.4

10.8

-

16.1

Taurine

18.4

14.7

-

22.1

2.30

1.84

-

2.76

Threonine

45.9

36.7

-

55.1

5.47

4.37

-

6.56

Tryptophane

16.9

13.5

-

20.2

3.44

2.75

-

4.13

Tyrosine

27.9

22.3

-

33.5

5.05

4.04

-

6.06

Valine

93.0

74.4

-

112

10.9

8.72

-

13.1

Substance

Control Level II
0472

Target Value

(µmol/l)

Range (µmol/l)

Target Value

(mg/l)

Range (mg/l)

1-Methylhistidine

7.71

6.17

-

9.25

1.30

1.04

-

1.57

α-Aminobutyric acid

49.3

39.5

-

59.2

5.09

4.07

-

6.10

β-Aminoisobutyric acid

21.3

17.0

-

25.5

2.19

1.75

-

2.63

3-Methylhistidine

45.3

36.2

-

54.3

7.66

6.13

-

9.19

4-Hydroxy-Proline

91.0

72.8

-

109

11.9

9.55

-

14.3

Acetyltyrosine

40.7

32.5

-

48.8

9.08

7.26

-

10.9

Adenosylhomocysteine

22.2

17.8

-

26.7

8.54

6.84

-

10.3

Alanine

655

524

-

786

58.4

46.7

-

70.1

Allo-Isoleucine

81.8

65.5

-

98.2

10.7

8.59

-

12.9

α-Aminoadipic acid

12.4

9.92

-

14.9

2.00

1.60

-

2.40

Anserine

9.56

7.65

-

11.5

2.30

1.84

-

2.76

Arginine

155

124

-

186

27.1

21.6

-

32.5

Argininosuccinic acid

74.6

59.7

-

89.6

21.7

17.3

-

26.0

Asparagine

121

97

-

145

16.1

12.9

-

19.4

Aspartic acid

126

101

-

152

16.7

13.3

-

20.0

β-Alanine

53.4

42.7

-

64.0

4.75

3.80

-

5.70

Carnosine

23.6

18.9

-

28.3

5.33

4.27

-

6.40

Citrulline

105

83.8

-

126

18.3

14.7

-

22.0

Cystathionine

25.1

20.1

-

30.1

5.57

4.46

-

6.69

Cysteinesulfate

26.5

21.2

-

31.8

5.33

4.26

-

6.39

Cystine

78.3

62.7

-

94.0

18.8

15.1

-

22.6

Ethanolamine

123

98

-

148

7.52

6.02

-

9.02

γ-Aminobutyric acid

9.97

7.98

-

12.0

1.03

0.822

-

1.23

Glutamine

935

748

-

1122

138

110

-

165

Glutamic acid

380

304

-

456

55.5

44.4

-

66.6

Glycine

646

517

-

775

48.5

38.8

-

58.2

Histidine

151

121

-

182

23.5

18.8

-

28.2

Homocitrulline

28.2

22.6

-

33.9

5.34

4.27

-

6.41

Homocystine

13.2

10.5

-

15.8

3.53

2.83

-

4.24

Hydroxylysine

17.8

14.3

-

21.4

2.89

2.31

-

3.47

Isoleucine

179

143

-

215

23.5

18.8

-

28.1

Leucine

298

239

-

358

39.1

31.3

-

47.0

Lysine

289

231

-

346

42.2

33.8

-

50.6

Methionine

80.9

64.8

-

97.1

12.1

9.66

-

14.5

Ornithine

202

161

-

242

26.6

21.3

-

32.0

Phenylalanine

310

248

-

373

51.3

41.0

-

61.5

Phosphoethanolamine

71.8

57.4

-

86.1

10.1

8.10

-

12.1

Phosphoserine

42.3

33.8

-

50.7

7.82

6.26

-

9.38

Pipecolic acid

16.7

13.4

-

20.0

2.16

1.73

-

2.59

Proline

336

268

-

403

38.6

30.9

-

46.4

Saccharopine

9.36

7.49

-

11.2

2.59

2.07

-

3.10

Sarcosine

16.9

13.5

-

20.3

1.51

1.21

-

1.81

Serine

369

295

-

443

38.8

31.0

-

46.5

Taurine

217

173

-

260

27.1

21.7

-

32.6

Threonine

253

203

-

304

30.2

24.2

-

36.2

Tryptophane

110

88.4

-

133

22.6

18.0

-

27.1

Tyrosine

162

129

-

194

29.3

23.5

-

35.2

Valine

320

256

-

384

37.5

30.0

-

45.0

Manual

Substance

Control Level III
0473

Target Value

(µmol/l)

Range (µmol/l)

Target Value

(mg/l)

Range (mg/l)

1-Methylhistidine

12.8

10.3

-

15.4

2.17

1.73

-

2.60

α-Aminobutyric acid

91.9

73.6

-

110

9.48

7.59

-

11.4

β-Aminoisobutyric acid

37.1

29.7

-

44.5

3.82

3.06

-

4.59

3-Methylhistidine

82.9

66.3

-

99.5

14.0

11.2

-

16.8

4-Hydroxy-Proline

170

136

-

204

22.3

17.9

-

26.8

Acetyltyrosine

73.1

58.5

-

87.7

16.3

13.1

-

19.6

Adenosylhomocysteine

40.6

32.5

-

48.8

15.6

12.5

-

18.7

Alanine

1112

890

-

1334

99.1

79.2

-

119

Allo-Isoleucine

160

128

-

192

21.0

16.8

-

25.2

α-Aminoadipic acid

18.4

14.7

-

22.1

2.96

2.37

-

3.56

Anserine

14.4

11.5

-

17.3

3.46

2.76

-

4.15

Arginine

297

237

-

356

51.7

41.3

-

62.0

Argininosuccinic acid

143

115

-

172

41.6

33.2

-

49.9

Asparagine

216

173

-

259

28.7

23.0

-

34.5

Aspartic acid

228

182

-

274

30.1

24.1

-

36.1

β-Alanine

92.5

74.0

-

111

8.24

6.59

-

9.89

Carnosine

36.5

29.2

-

43.8

8.27

6.61

-

9.92

Citrulline

191

153

-

230

33.5

26.8

-

40.2

Cystathionine

44.1

35.3

-

52.9

9.80

7.84

-

11.8

Cysteinesulfate

38.9

31.1

-

46.7

7.83

6.26

-

9.39

Cystine

145

116

-

174

34.9

27.9

-

41.9

Ethanolamine

228

182

-

273

13.9

11.1

-

16.7

γ-Aminobutyric acid

15.0

12.0

-

17.9

1.54

1.23

-

1.85

Glutamine

1512

1209

-

1814

222

178

-

267

Glutamic acid

691

553

-

829

101

80.8

-

121

Glycine

1079

864

-

1295

81.0

64.8

-

97.2

Histidine

263

210

-

316

40.08

32.7

-

49.0

Homocitrulline

46.4

37.1

-

55.6

8.77

7.02

-

10.5

Homocystine

22.5

18.0

-

27.0

6.03

4.83

-

7.24

Hydroxylysine

30.4

24.3

-

36.5

4.94

3.95

-

5.92

Isoleucine

325

260

-

389

42.6

34.1

-

51.1

Leucine

555

444

-

666

72.8

58.3

-

87.4

Lysine

546

436

-

655

79.8

63.8

-

95.7

Methionine

151

121

-

181

22.5

18.0

-

27.0

Ornithine

376

301

-

452

49.7

39.8

-

59.7

Phenylalanine

576

461

-

692

95.2

76.2

-

114

Phosphoethanolamine

132

105

-

158

18.6

14.8

-

22.3

Phosphoserine

77.9

62.3

-

93.5

14.4

11.5

-

17.3

Pipecolic acid

30.7

24.6

-

36.9

3.97

3.18

-

4.76

Proline

602

482

-

722

69.3

55.4

-

83.2

Saccharopine

13.8

11.1

-

16.6

3.82

3.06

-

4.58

Sarcosine

29.6

23.7

-

35.5

2.63

2.11

-

3.16

Serine

605

484

-

726

63.6

50.9

-

76.3

Taurine

407

325

-

488

50.9

40.7

-

61.1

Threonine

458

366

-

549

54.5

43.6

-

65.4

Tryptophane

198

158

-

237

40.3

32.3

-

48.4

Tyrosine

290

232

-

348

52.6

42.1

-

63.1

Valine

553

442

-

664

64.8

51.8

-

77.8

Reconstitution

Carefully remove the rubber stopper from the vial. Add exactly 1.0 ml of distilled water into the vial. Replace the stopper and allow to sit for 10 to 15 minutes at room temperature. Swirl the vial to dissolve the contents until homogeneity

Storage conditions

Stored below -18 °C unopened controls are stable until the expiry date which is stated on the vial labels. The reconstituted controls can be stored up to 1 day tightly capped and light protected at +2 to +8 °C. If the controls cannot be analysed within this period, it should be aliquoted and stored frozen below -18 °C (up to 3 months).