Imatinib/Norimatinib/Dasatinib/Nilotinib Plasma Controls

Imatinib/Norimatinib/Dasatinib/Nilotinib Plasma Controls

   
  • Dasatinib
  • Imatinib
  • Nilotinib
  • Norimatinib

Order no.: 0224/0225/0226

Product Name Qty
Imatinib/Norimatinib/Dasatinib/Nilotinib Plasma Control, Level I
Order no.: 0225
Imatinib/Norimatinib/Dasatinib/Nilotinib Plasma Control, Level II
Order no.: 0226
Imatinib/Norimatinib/Dasatinib/Nilotinib Plasma Control, Bi-Level (I+II)
Order no.: 0224

Description

Imatinib/Norimatinib/Dasatinib/Nilotinib Plasma Controls, lyophilised

0224 Imatinib/Norimatinib/Dasatinib/Nilotinib Plasma Control, Bi-Level I + II (lyoph.), 2 x 5 x 2 ml
0225 Imatinib/Norimatinib/Dasatinib/Nilotinib Plasma Control, Level I (lyoph.), 5 x 2 ml
0226 Imatinib/Norimatinib/Dasatinib/Nilotinib Plasma Control, Level II (lyoph.), 5 x 2 ml

These lyophilised quality controls from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to monitor the accuracy and precision of analytical procedures in clinical diagnostics for the quantitative determination of imatinib, norimatinib, dasatinib and nilotinib in serum/plasma. While following the instructions the controls should be handled and measured in the same manner as a patient specimen.

Technical Data

Method of Analysis

HPLC

Parameter

Dasatinib, Imatinib, Nilotinib, Norimatinib

Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

Substance
Unit
Value Level I
Range Level I
Value Level II
Range Level II
Imatinib
µg/l
nmol/l
933
1891
747-1120
1513-2269
1880
3810
1504-2256
3048-4571
Norimatinib
µg/l
nmol/l
168
350
134-201
280-420
310
645
248-371
516-775
Dasatinib
µg/l
nmol/l
114
233
91-137
187-280
241
493
193-289
395-592
Nilotinib
µg/l
nmol/l
749
1414
599-899
1131-1697
1215
2296
972-1458
1837-2755

Reconstitution

Carefully remove the metal seal and rubber stopper from the vials. Add exactly 2.0 ml of distilled water into each vial. Return the stopper and incubate for 10 to 15 minutes at room temperature. Swirl the vials to dissolve the contents until homogeneity.

Storage conditions

Stored below -18 °C and unopened, the lyophilised controls are stable until the expiry date specified on the vial labels. The reconstituted controls can be stored up to 3 weeks tightly capped at +2 to +8 C. If the controls cannot be used within this period, they should be aliquoted and stored frozen below -18 °C (up to 3 months). For more details about storage conditions please check your instruction manual.