AED Serum Controls

AED Serum Controls

   

Order no.: 0160/RUO; 0170/RUO; 0180/RUO; 0188/RUO

Product Name Qty
AED Serum Control, Level I
Order no.: 0160/RUO
AED Serum Control, Level II
Order no.: 0170/RUO
AED Serum Control, Level III
Order no.: 0180/RUO
AED Serum Control, Tri-Level (I+II+III)
Order no.: 0188/RUO

Description

AED Serum Controls, lyophilised

0160/RUO AED Serum Control, Level I (lyoph.), 10 x 5 ml
0170/RUO AED Serum Control, Level II (lyoph.), 10 x 5 ml
0180/RUO AED Serum Control, Level III (lyoph.), 10 x 5 ml
0188/RUO AED Serum Control, Tri-Level I + II + III (lyoph.), 2 x 3 x 5 ml and 1 x 4 x 5 ml

These lyophilised Chromsystems controls are based on human serum and should be used according to the instruction manual. They are designed to monitor the accuracy and precision of analytical procedures for the quantitative determination of antiepileptic drugs. While following the instructions the controls should be handled and measured in the same manner as research samples.

Technical Data

Method of Analysis

HPLC

Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly.

 Level I (0160/RUO)Level II (0170/RUO)Level III (0180/RUO)
SubstanceUnitSuggested valueSuggested rangeSuggested valueSuggested rangeSuggested valueSuggested range
Ethosuximide mg/l
µmol/l
43.3
307
34.7-52.0
245-368
93.2
660
74.6-112.0
528-792
113
797
90.1-135
638-957
Primidone mg/l
µmol/l
4.39
20.1
3.51-5.27
16.1-24.1
19.6
90.0
15.7-23.6
72.0-108
29.0
133
23.2-34.8
106-159
Phenobarbital mg/l
µmol/l
10.0
43.3
8.03-12.1
34.6-51.9
40.3
173
32.2-48.3
139-208
46.6
201
37.3-55.9
161-241
Carbamazepine
-10, 11-epoxide
mg/l
µmol/l
1.92
7.60
1.54-2.30
6.08-9.12
5.41
21.4
4.33-6.49
17.1-25.7
7.66
30.3
6.13-9.19
24.3-36.4
Lamotrigine mg/l
µmol/l
2.87
11.2
2.29-3.44
8.95-13.4
10.7
41.7
8.55-12.8
33.4-50.0
14.9
58.2
11.9-17.9
46.6-69.9
Phenytoin mg/l
µmol/l
4.79
19.0
3.83-5.72
15.2-22.8
19.5
77.1
15.6-23.4
61.6-92.5
28.8
114
23.0-34.5
91.1-137
Carbamazepine mg/l
µmol/l
4.72
20.0
3.77-5.66
16.0-23.9
14.5
61.2
11.6-17.4
48.9-73.4
19.1
80.7
15.3-22.9
64.6-96.9

Reconstitution

Carefully remove the metal seal and rubber stopper from the vials. (Caution when removing the metal seal: risk of injuries due to sharp cutting edges!). Add exactly 5.0 ml of distilled water into each vial. Return the stopper and incubate for 10 to 15 minutes at room temperature. Swirl the vials to dissolve the contents until homogeneity.

Storage conditions

Stored at +2 to +8 °C and unopened, the lyophilised controls are stable until the expiry date specified on the vial labels. The reconstituted controls can be stored up to 2 weeks light protected and tightly capped at +2 to +8 C. If the controls cannot be used within this period, they should be aliquoted and stored frozen below –18 °C (up to 3 months). For more details about storage conditions please check your instruction manual.