92111_1000F LCMS TDM series A basic kit automation

BASIC Kit A for 1000 tests with 96 Well Filter Plates - LC-MS/MS

Order no.: 92111/1000/F
1000 Tests

Part of the MassTox® TDM Series A
Unique modular system for therapeutic drug monitoring
Provides all components required for automated sample prep and all mobile phases

Description

The BASIC Kit A is a part of the Series A modular system, which enables the analysis of more than 170 parameters without switching column or changing the mobile phases, thereby minimising the required workload in the laboratory. The Basic Kit A contains all components required for sample preparation and all necessary mobile phases.

This Chromsystems kit enables the automation of the BASIC Kit.

In addition to the automated version Chromsystems also offers a standard version for manual processing of the BASIC Kit A with 200 and 1000 analyses.

 

Further component of the modular system is the MasterColumn® A, an analytical column used for the determination of all Series A analytes. Different Parameter Sets can be selected depending on the drug category – the portfolio covers 13 sets for the determination of more than 170 substances and metabolites.

 

Content

3 x Mobile Phase 1 (92001)
3 x Mobile Phase 2 (92002)
5 x Extraction Buffer (92005)
5 x Dilution Buffer 1 (92007)
5 x Dilution Buffer 2 (92008)
2 x Rinsing Solution (92009)
1 x Precipitation Reagent (92012)
4 x 96 well filter plates (92057)
8 x 96 well collection plates (92058)
4 x Pierceable adhesive seals (92059)

Technical Data

Method of Analysis

LC-MS/MS

Number of Tests

1000

Sample Preparation

  • Pipette 25 µl Extraktion Buffer into a 96 well filter plate (order no. 92057).
  • Add 50 µl sample/calibrator/MassCheck® control.
  • Shake 2 min (1200 rpm).
  • Add 250 µl reconstituted Internal Standard Mix.
  • Shake 40 s (700 rpm).
  • Separate precipitate by centrifugation ( 2000 x g, 1 min) and collect the eluate in a collection plate (order no. 92058).
  • Dilute eluate with Dilution Buffer, instrument and parameter set specific, in an additional collection plate.
  • Seal collection plate with pierceable adhesive seal (order no. 92059) and transfer to autosampler.
  • Inject eluate into the LC-MS/MS system.

Please note

The freely available information on this website, in particular on the sample preparation, are not sufficient to work with our products. Please read instructions and warning notices on products and/or instruction manuals.

Kit Components

Components available separately

Mobile Phase 1


Order no.: 92001

Mobile Phase 2


Order no.: 92002

Extraction Buffer


Order no.: 92005

Dilution Buffer 1


Order no.: 92007

Dilution Buffer 2


Order no.: 92008

Rinsing Solution


Order no.: 92009

Precipitation Reagent


Order no.: 92012

96 Well Filter Plates


Order no.: 92057