Newborn Screening

 

 

NEW: Assay Upgrades for Newborn Screening
Succinylacetone now also for underivatised methods

 

Succinylacetone is a primary marker to detect tyrosinemia type I in newborns. In many countries it is part of the newborn screening programs. With our new assay upgrades you have the opportunity to screen for succinylacetone also with the more time efficient underivatised methods.

 

All Chromsystems' assays allow the fast and reliable determination of amino acids and acylcarnitines from dried blood spot samples as part of the newborn screening for amino acid and fatty acid metabolic disorders using tandem mass spectrometry. Learn more about the respective assays and find most of their advantages below:

 

  • • CE-IVD validated and ready-to-use assays by LC-MS/MS
  • • Each analyte safeguarded by its own internal standard
  • • Fast and robust sample preparation
  • • Screening for many metabolic disorders in a single run such as PKU (Phenylketonuria), MSUD (Maple Syrup Urine Disease) and tyrosinemia type I

 

There are several solutions available for any requirements: with well plates or well filter plates, derivatised or underivatised methods and succinylacetone upgrade sets.
Please find out more details in our brochure.

 

Assay Overview

 

WITH DERIVATISATION

WITHOUT DERIVATISATION

Assay No.

55000

55000/F

57000

57000/F

Method

96 Well Plates

96 Well Filter Plates

96 Well Plates

96 Well Filter Plates

Parameters

Amino Acids + Acylcarnitines

Amino Acids + Acylcarnitines

Amino Acids + Acylcarnitines

Amino Acids + Acylcarnitines

Number of tests

960

960

960

960

Assay Characteristics

Highest sensitivity and extremely low interferences

 

 

 

 

55111 Succinylacetone Upgrade Set

Highest sensitivity and extremely low interferences

 

One pipetting step can be saved by using well filter plates

Efficient and time-saving sample preparation

 

 

 

 

NEW: 57111 Succinylacetone Upgrade Set

Efficient and time-saving sample preparation

 

One pipetting step can be saved by using well filter plates

 

NEW: 57111/F Succinylacetone Upgrade Set

 

 

Download Brochure

 

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Brochure Newborn Screening

 

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