0213XT 0214XT 0215XT LCMS TDM Series A controls antidepressants1_XT

MassCheck® Antidepressants 1/EXTENDED Plasma Controls

   
  • Citalopram
  • Desmethylfluoxetine
  • Duloxetine
  • Fluoxetine
  • Fluvoxamine
  • Mirtazapine
  • N-Desmethylcitalopram
  • N-Desmethylmirtazapine
  • N-Desmethylsertraline
  • O-Desmethylvenlafaxine
  • Paroxetine
  • Sertraline
  • Venlafaxine

Order no.: 0213XT/0214XT/0215XT

MassTox® TDM Series A

Product Name Qty
MassCheck® Antidepressants 1/EXTENDED Plasma Control, Level I
Order no.: 0214/XT
MassCheck® Antidepressants 1/EXTENDED Plasma Control, Level II
Order no.: 0215/XT
MassCheck® Antidepressants 1/EXTENDED Plasma Control, Bi-Level (I+II)
Order no.: 0213/XT

Description

MassCheck® Antidepressants 1/EXTENDED, lyophilised.
For MassTox® TDM Series A Parameter Set Antidepressants 1/EXTENDED in Serum/Plasma.

0213/XT MassCheck® Antidepressants 1/EXTENDED Plasma Control, Bi-Level I + II (lyoph.), 2 x 5 x 1 ml
0214/XT MassCheck® Antidepressants 1/EXTENDED Plasma Control, Level I (lyoph.), 5 x 1 ml
0215/XT MassCheck® Antidepressants 1/EXTENDED Plasma Control, Level II (lyoph.), 5 x 1 ml

These lyophilised quality controls from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to monitor the accuracy and precision of analytical procedures in clinical diagnostics for the quantitative determination of antidepressants 1/Extended in serum/plasma. While following the instructions the controls should be handled and measured in the same manner as a patient specimen.

Technical Data

Method of Analysis

LC-MS/MS

Parameter

Citalopram, Desmethylfluoxetine, Duloxetine, Fluoxetine, Fluvoxamine, Mirtazapine, N-Desmethylcitalopram, N-Desmethylmirtazapine, N-Desmethylsertraline, O-Desmethylvenlafaxine, Paroxetine, Sertraline, Venlafaxine

Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

SubstanceValue [µg/l]
Level I
Range [µg/l]
Level I
Value [µg/l]
Level II
Range [µg/l]
Level II
O-desmethylvenlafaxine 209 167-251 349 279-419
Mirtazapine 107 85.4-128 201 160-241
N-Desmethylmirtazapin 108 86.4-130 211 169-253
Venlafaxine 82.3 65.8-99 131 105-158
Citalopram 70.8 56.6-85.0 133 106-160
N-Desmethylcitalopram 78.6 62.9-94.3 146 117-175
Paroxetine 53.3 42.6-64.0 77.5 62.0-93.0
Desmethylfluoxetine 280 224-336 403 323-484
Fluoxetine 228 182-274 360 288-432
Fluvoxamine 122 97.6-146 192 154-230
Duloxetine 16.5 13.2-19.8 120 96.0-144
Sertraline 54.1 43.3-64.9 104 83.2-125
N-Desmethylsertraline 90.9 72.7-109 167 134-200

Reconstitution

Carefully remove the rubber stopper from the vials. Add exactly 1.0 ml of distilled water into each vial. Return the stopper and incubate for 10 to 15 minutes at room temperature. Swirl the vials to dissolve the contents until homogeneity.

Storage conditions

Stored below -18 °C and unopened, the lyophilised controls are stable until the expiry date specified on the vial labels. The reconstituted controls can be stored up to 2 weeks light protected and tightly capped at +2 to +8 C. If the controls cannot be used within this period, they should be aliquoted and stored frozen below -18 °C (up to 3 months). For more details about storage conditions please check your instruction manual.