Basic Kit A for 1000 Tests with 96 Well Filter Plates - LC-MS/MS

Order No.: 92111/1000/F, for 1000 tests
Parameters:
28 grouped in 2 sets

Part of the MassTox® TDM Series A
Modular system for therapeutic drug monitoring
Provides all components required for sample prep and all mobile phases
Sample preparation with 96 Well Filter Plates

CE-IVD validated product ready for IVDR within timeframes and transition periods specified by the IVDR 2017/746

Antiepileptic Drugs (92921)

Carbamazepine, Carbamazepine-10,11-epoxide, 10-OH-Carbamazepine, 10,11-Dihydroxycarbamazepine, N-Desmethylmesuximide, Ethosuximide, Felbamate, Gabapentin, Lacosamide, Lamotrigine, Levetiracetam, Oxcarbazepine, Phenobarbital, Phenylethylmalonamide (PEMA), Phenytoin, Pregabalin, Primidone, Rufinamide, Stiripentol, Sultiame, Theophylline, Tiagabine, Topiramate, Valproic acid, Vigabatrin, Zonisamide

Mycophenolic Acid (92916)

Mycophenolic acid, Mycophenolic acid glucuronide

The Basic Kit A is a part of the Series A modular system, which enables the analysis of many parameters without switching column or changing the mobile phases, thereby minimising the required workload in the laboratory. The Basic Kit A contains all components required for sample preparation and all necessary mobile phases.

Further component of the modular system is the MasterColumn® A, an analytical column used for the determination of all Series A analytes.

 

Content

  • 3 x Mobile Phase 1, 1000 ml
  • 3 x Mobile Phase 2, 1000 ml
  • 5 x Extraction Buffer, 5 ml
  • 5 x Dilution Buffer 1, 50 ml
  • 5 x Dilution Buffer 2, 50 ml
  • 2 x Rinsing Solution, 1000 ml
  • 1 x Precipitation Reagent, 250 ml
  • 4 x 96 Well Filter Plates, 3 pcs.
  • 8 x 96 Well Collection Plates, 3 pcs.
  • 4 x Pierceable Adhesive Seals, 3 pcs.
More Information
Method of Analysis LC-MS/MS
Number of Tests 1000
Please note The information listed here, including the sample preparation, is not sufficient for using the product. Please read the information provided in the instruction manual, which includes detailed information on limitations associated with the use of the product in line with its intended purpose.
Sample Preparation

The information on the sample preparation presented here is not sufficient for use in the laboratory. For a detailed step by step description, please refer to the instruction manual.

  • Pipette 25 µl Extraction Buffer into 96 well filter plate.
  • Add 50 µl sample/calibrator/MassCheck® control and shake 2 min.
  • Add 250 µl reconstituted Internal Standard Mix and shake 40 s .
  • Separate precipitate by centrifugation (2000 x g, 1 min) and collect the eluate in collection plate.
  • Dilute eluate with Dilution Buffer, instrument and parameter set specific, in an additional collection plate.
  • Seal collection plate with pierceable adhesive seal and transfer to autosampler.
  • Inject eluate into the LC-MS/MS system.
Parameters 28 grouped in 2 sets
The following components are included in the kit:
As a customer please login or register to gain full access.

Antiepileptic Drugs (92921)

Carbamazepine, Carbamazepine-10,11-epoxide, 10-OH-Carbamazepine, 10,11-Dihydroxycarbamazepine, N-Desmethylmesuximide, Ethosuximide, Felbamate, Gabapentin, Lacosamide, Lamotrigine, Levetiracetam, Oxcarbazepine, Phenobarbital, Phenylethylmalonamide (PEMA), Phenytoin, Pregabalin, Primidone, Rufinamide, Stiripentol, Sultiame, Theophylline, Tiagabine, Topiramate, Valproic acid, Vigabatrin, Zonisamide

Mycophenolic Acid (92916)

Mycophenolic acid, Mycophenolic acid glucuronide

The Basic Kit A is a part of the Series A modular system, which enables the analysis of many parameters without switching column or changing the mobile phases, thereby minimising the required workload in the laboratory. The Basic Kit A contains all components required for sample preparation and all necessary mobile phases.

Further component of the modular system is the MasterColumn® A, an analytical column used for the determination of all Series A analytes.

 

Content

  • 3 x Mobile Phase 1, 1000 ml
  • 3 x Mobile Phase 2, 1000 ml
  • 5 x Extraction Buffer, 5 ml
  • 5 x Dilution Buffer 1, 50 ml
  • 5 x Dilution Buffer 2, 50 ml
  • 2 x Rinsing Solution, 1000 ml
  • 1 x Precipitation Reagent, 250 ml
  • 4 x 96 Well Filter Plates, 3 pcs.
  • 8 x 96 Well Collection Plates, 3 pcs.
  • 4 x Pierceable Adhesive Seals, 3 pcs.
More Information
Method of Analysis LC-MS/MS
Number of Tests 1000
Please note The information listed here, including the sample preparation, is not sufficient for using the product. Please read the information provided in the instruction manual, which includes detailed information on limitations associated with the use of the product in line with its intended purpose.
Sample Preparation

The information on the sample preparation presented here is not sufficient for use in the laboratory. For a detailed step by step description, please refer to the instruction manual.

  • Pipette 25 µl Extraction Buffer into 96 well filter plate.
  • Add 50 µl sample/calibrator/MassCheck® control and shake 2 min.
  • Add 250 µl reconstituted Internal Standard Mix and shake 40 s .
  • Separate precipitate by centrifugation (2000 x g, 1 min) and collect the eluate in collection plate.
  • Dilute eluate with Dilution Buffer, instrument and parameter set specific, in an additional collection plate.
  • Seal collection plate with pierceable adhesive seal and transfer to autosampler.
  • Inject eluate into the LC-MS/MS system.
Parameters 28 grouped in 2 sets
The following components are included in the kit:
As a customer please login or register to gain full access.