22005 HPLC serum calibration standard antiepileptic drugs

AED Serum Calibration Standard

Order no.: 22005
  • 10-OH-carbamazepine
  • Carbamazepine
  • Carbamazepine-10,11-epoxide
  • Ethosuximide
  • Lamotrigine
  • Oxcarbamazepine (Trileptal┬«)
  • Phenobarbital
  • Phenytoin
  • Primidone
  • Sultiame
  • Zonisamide
Antiepileptic Drugs in Serum/Plasma - HPLC

Description

AED Serum Calibration Standard, lyophilised. This product is suitable for the kits with the ordering number 22000/F and 22000/HR.

This lyophilised calibrator from Chromsystems is based on human serum and should be used according to the instruction manual. It is designed to calibrate the measurement method in clinical diagnostics for the quantitative determination of antiepileptic drugs in serum/plasma. While following the instructions the calibrator should be handled and measured in the same manner as a patient specimen.

Technical Data

Method of Analysis

HPLC

Content

5 x 1 ml (lyoph.)

Parameter

10-OH-carbamazepine, Carbamazepine, Carbamazepine-10,11-epoxide, Ethosuximide, Lamotrigine, Oxcarbamazepine (Trileptal®), Phenobarbital, Phenytoin, Primidone, Sultiame, Zonisamide

Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

SubstanceUnitValue
Ethosuximide mg/l
µmol/l
57.8
409
Primidone mg/l
µmol/l
9.19
42.1
Lamotrigine mg/l
µmol/l
7.04
27.5
Phenobarbital mg/l
µmol/l
23.3
100
Carbamazepine-10,11-epoxide mg/l
µmol/l
2.73
10.8
Carbamazepine mg/l
µmol/l
9.39
39.7
Phenytoin mg/l
µmol/l
11.8
46.8

Reconstitution

Carefully remove the metal seal and rubber stopper from the vials. Add exactly 1.0 ml of distilled water into each vial. Return the stopper and incubate for 10 to 15 minutes at room temperature. Swirl the vials to dissolve the contents until homogeneity.

Storage conditions

Stored at +2 to +8 °C and unopened, the lyophilised calibrator is stable until the expiry date specified on the vial labels. The reconstituted calibrator can be stored up to 2 weeks light protected and tightly capped at +2 to +8 C. If the calibrator cannot be used within this period, it should be aliquoted and stored frozen below -18 °C (up to 3 months). For more details about storage conditions please check your instruction manual.