27029 HPLC 3PLUS1 Multilevel Plasma Calibrator Set Itraconazole PosaconazoleVoriconazole

3PLUS1® Multilevel Plasma Calibrator Set Itraconazole/Posaconazole/Voriconazole

Order no.: 27029
  • Hydroxyitraconazole
  • Itraconazole
  • Posaconazole
  • Voriconazole
Itraconazole, Posaconazole and Voriconazole in Serum/Plasma - HPLC

Description

 3PLUS1® Multilevel Plasma Calibrator Set for Itraconazole/Posaconazole/Voriconazole, lyophilised

These lyophilised calibrators from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed according to the recommendations of the FDA to calibrate the measurement method in clinical diagnostics for the quantitative determination of itraconazole, posaconazole and voriconazole in serum/plasma. While following the instructions the calibrators should be handled and measured in the same manner as a patient specimen.
These calibrators are only available as multilevel calibrator set with 3 different concentration levels plus 1 blank value.

Technical Data

Method of Analysis

HPLC

Content

4 x 1 ml (lyoph.)

Parameter

Hydroxyitraconazole, Itraconazole, Posaconazole, Voriconazole

Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

Substance Calibrator 1
(mg/l)
Calibrator 2
(mg/l)
Calibrator 3
(mg/l)
Blank Calibrator
(mg/l)
Itraconazole 0.19 0.88 1.95 n.d.
Hydroxy-Itraconazole 0.28 1.14 2.86 n.d.
Posaconazole 0.30 2.43 5.88 n.d.
Voriconazole 0.83 2.81 5.76 n.d.

 n.d. = not detected (< LOQ)

Reconstitution

Carefully remove the metal seal and rubber stopper from the vials. Add exactly 1.0 ml of distilled water into each vial. Return the stopper and incubate for 10 to 15 minutes at room temperature. Swirl the vials to dissolve the contents until homogeneity.

Storage conditions

Stored below -18 °C and unopened, the lyophilised calibrators are stable until the expiry date specified on the vial labels. The reconstituted calibrators can be stored up to 4 weeks tightly capped at +2 to +8 C. If the calibrators cannot be used within this period, they should be aliquoted and stored frozen below -18 °C (up to 3 months). For more details about storage conditions please check your instruction manual.